However, the meta-analysis presented some limitations, including the analysis of only anti-thyroperoxidase antibodies, which are not the unique auto-antibody of autoimmune thyroid diseases and, in contrast, are not sufficient to make diagnosis of thyroid autoimmunity (they can be found in subacute thyroid autoimmunuty and in non-autoimmune disorders) [44]. The gene discussed is TPO; the disease is autoimmune thyroid disease.