The etiology of AMD remains largely unknown, but it has been suggested that an equilibrium between proangiogenic vascular endothelial growth factor (VEGF) and antiangiogenic neurotrophic pigment epithelium-derived factor (PEDF) is important for regulation of retinal physiology and for pathophysiology, including late AMD [5,6,7]. This evidence concerns the gene VEGFA and age-related macular degeneration.