With statins being characterized in vitro to induce apoptosis in several hematologic as well as solid tumor cell lines [26,27], the inhibitory effect of statins on distinct cellular pathways could be demonstrated: in HNSCC cell lines for instance, lovastatin inhibited epithelial growth factor receptor (EGFR) dimerization and internalization, with thereby presenting a further potential pharmacological cellular target [28]. The gene discussed is EGFR; the disease is head and neck squamous cell carcinoma.