They created a LQTS2 (KCNH2 p.(Ala614Val)) and CPVT2 (CASQ2 p.(Asp307His)) (Table 2) model and using voltage and calcium dyes, AP prolongation in LQTS iPSC-CM was revealed while the CPVT cell model showed abnormal calcium transients and more arrhythmias under stress conditions, indicating that these EHT models can be used to study channelopathies. This evidence concerns the gene CASQ2 and catecholaminergic polymorphic ventricular tachycardia.