Genes negatively correlated with MATR3, including GADD45GIP1, MRPL23 (RPL23L), MRPL41, MRPS15, RPS15, NDUFS8, C19orf53, BLOC1S1, and SERF2 were all significantly associated with poor OS when overexpressed in ccRCC (Figure S4). This evidence concerns the gene C19orf53 and nonpapillary renal cell carcinoma.