ACE2 and COVID-19: Table 1 describes the docking scores of the constituents. The receptor—ligand interaction diagrams of the best docked compound hesperidin against the promising targets of COVID-19 (docking score against Mpro: −9.59 kcal/mol, spike-ACE2 RBD: −9.25 kcal/mol and RdRp: −8.91 kcal/mol) are shown in Figure 2.