AGT and cardiac hypertrophy: Thus, this study evaluated the role of FKBPL in the development of cardiac hypertrophy and HFpEF using in vitro models of cardiomyoblasts exposed to a hypertensive stimulus, angiotensin-II (Ang-II), and/or the FKBPL mimetic AD-01, as well as human plasma samples from people with different forms of HFpEF and controls.