hnRNP H drives an oncogenic switch in glioblastoma multiforme (GBM) cells by promoting of aberrant splicing of MADD and RON [32], whereas H1/H2-mediated unsplicing of thymidine phosphorylase results in antitumor drug resistance in leukemia cells [33]. The gene discussed is HNRNPH2; the disease is glioblastoma.