LCN2 and chronic kidney disease: Kaplan-Meier survival curves demonstrated statistically significant differences in survival distribution for tertiles of plasma NGAL concentrations and the risk of new-onset CKD, for the composite outcome (p = 0.006, log-rank test) and for new-onset CKD defined solely by eGFR (p < 0.001, log-rank), but not for new-onset CKD defined by UAE (p = 0.164, log-rank) (Figure 2).