CD4 and head and neck squamous cell carcinoma: We found that the higher expression of CAV1 was negatively correlated with T cell regulatory (Tregs) (partial.cor = −0.341 p = 6.82 × 10−15) and positively correlated with CD8 + T cells (partial.cor = 0.383 p = 1.36 × 10−18), CD4 + T cells (partial.cor = 0.285 p = 1.19 × 10−10) and B cells (partial.cor = 0.164 p = 2.65 × 10−4) via searching the relationship between the expression levels of CAV1 and CAV2 and the infiltration degree of different types of cells in immune microenvironment in HNSCC.