Autoradiography analysis of AD hippocampal sections with [11C]THK-951 (Figure 3a) showed high binding in the CA1 region of the hippocampus, in a pattern matching with [18F]THK-523 (Figure 2f) binding and tau immunohistochemistry (IHC), but distinct from that of Aβ. The gene discussed is MAPT; the disease is Alzheimer disease.