A series of genes in the TRP family including TRPC1, TRPC4, TRPC6, TRPM2, TRPM4, TRPM7, TRPV2, TRPV4, MCOLN1, MCOLN2, MCOLN3, PKD2, and PKDL1 were highly expressed in all cancer types. The gene discussed is TRPM4; the disease is cancer.