Heterozygous PtenF341V/+ mice, though, developed a similar but not overlapping tumor profile as germline Pten heterozygous mice with mammary tissue, thymus, adrenal gland, and stomach cancers observed, but an absence of uterine, thyroid, and prostate cancers observed in Pten+/− mice [34,50]. Here, PTEN is linked to Familial prostate cancer.