Figure 3 illustrates that 46% of NSCLC patients, compared to 22.5% of SCLC had no basal risk factor with respect to the five risk factors “brain/liver metastasis, high NLR, high amount of HLA-DRlow MDSC, low frequency of slan+ non-classical monocytes and of CD1c+ MDC (cut-off values of SCLC). Otherwise, 45% of SCLC patients, compared to only 24% of NSCLC patients, had three–five risk factors. Both in SCLC and NSCLC, the neutrophil numbers were directly correlated with monocyte counts, especially with the frequency of HLA-DRlow MDSC. This evidence concerns the gene SECISBP2L and non-small cell lung carcinoma.