When talking about DM and pancreatitis, two MMPs deserve special attention: MMP-2 and MMP-9 (gelatinases A and B, respectively), responsible for the degradation of gelatins, type III, IV, V, VII, X, and XI collagens, fibronectin, laminin, elastin, aggrecan, entactin, and vitronectin [63]. This evidence concerns the gene MMP2 and diabetes mellitus.