Moreover, I established radioresistant breast cancer models (MCF-7R and MDAMB231R) from MCF-7 and MDAMB231 cells and used a combined treatment with nodakenin and radiation to overcome radioresistance through the suppression of the EMT process, indicating the inhibition of E-cadherin and the enhancement of vimentin and N-cadherin. The gene discussed is CDH1; the disease is breast cancer.