The anti-cancer effect of strawberry-derived phenolic extracts has been mainly correlated to the ability of phenolic compounds to reduce the levels of reactive oxygen species (ROS) and oxidative DNA damage, to detoxify carcinogens, and to inhibit cancer cell proliferation inducing apoptosis and cell-cycle arrest modulating key pathways such as the activator protein-1, NF-κB, PI3K, and inhibiting the Wnt signaling [22,25,26]. Here, NFKB1 is linked to cancer.