LEP and gestational diabetes: In a study realized on a high-fat diet GDM mice model, resveratrol supplementation (0.2%) managed to ameliorate glucose uptake and lipid metabolism, regulating the miR-23a-3p/NOV axis through the increase in Adiponectin, Leptin, Phosphoinositide 3-kinase (p-PI3K), and phosphorylated Akt (p-Akt) in adipocytes with IR and parallelly decreasing the nephroblastoma (NOV) overexpression [128].