NFKB1 and diabetes mellitus: Garlic sartan isopropyl ester inhibits the NF-κB signaling pathway through the activation of SIRT1/Nrf2, reduces the expressions of NF-κB p65 and inflammatory cytokines TNF-α and IL-1β, and attenuates diabetes-induced oxidative stress and inflammation in high-fat and STZ-induced rats [30].