The data compared using the median of anisocytosis showed that the patients with more than 12.8 presented were older men with significantly high levels of LDH, CRP, creatinine, leukocytes, neutrophils, NLR, and FIB-4, as well as lower levels of prothrombin time, platelets, hemoglobin, and eosinophils and significantly more cases of diabetes, cardiovascular disease, anemia, liver disease, endocrine disease, other respiratory disease, kidney disease, and hypertension (Table 4). This evidence concerns the gene CRP and endocrine system disorder.