Two upregulated TFs (STAT1 and LTF) and 10 downregulated TFs (RORC, EGR1, NFIL3, NFATC1, RELA (p65), IKZF1, IKZF2, ETS1, GFI1, and CEBPB) were identified in the tubulointerstitium of LN (Figure 3C). The gene discussed is GFI1; the disease is lobular neoplasia.