Two upregulated TFs (STAT1 and LTF) and 10 downregulated TFs (RORC, EGR1, NFIL3, NFATC1, RELA (p65), IKZF1, IKZF2, ETS1, GFI1, and CEBPB) were identified in the tubulointerstitium of LN (Figure 3C). Here, EGR1 is linked to lobular neoplasia.