We identified two transcription factors (STAT1 and LTF) that were positively correlated with T-cell subset infiltration in the lupus tubulointerstitium, and three transcription factors (IRF8, RORC and IKZF2) that were positively associated with T-cell subset infiltration in the glomeruli. The gene discussed is IRF8; the disease is systemic lupus erythematosus.