Neuronal L1 cell adhesion molecule (L1CAM; CD171) is expressed in virtually all neuroblastomas in addition to neuroendocrine tumours, small cell lung carcinoma, melanoma, glioblastoma multiforme, sarcomas, ovarian serous cancer, colon cancer, renal cell carcinoma, prostate cancer and malignant mesothelioma. The gene discussed is L1CAM; the disease is neuroblastoma.