For example, in the study of the CHGA 3′UTR variant C + 87T (rs7610), Zhang et al. [37] found that miR-107 has a sequence complementary to CHGA 3′UTR and the expression level of CHGA in human neuroblastoma cells is opposite to the expression level of miR-107, and then verified that miR-107 can inhibit CHGA expression by targeting its 3′UTR using double luciferase reporter system. The gene discussed is CHGA; the disease is neuroblastoma.