They identified EGFR as a specific pleural effusion exosomes protein of NSCLC, as well as other EGFR interacting proteins (e.g., Grb2, calmodulin, CD59, and Rab5), which is in line with similar findings in various types of human body fluids including colorectal cancer ascites and urine [42,43]. Here, EGFR is linked to non-small cell lung carcinoma.