VWF and laryngotracheoesophageal cleft: In addition, ADAMTS13:AC, VWF:Ag, and the VWF:Ag/ADAMTS13:AC levels were decreased, increased, and increased, respectively, according to LC progression [2,8,9,12], and high VWF:Ag and low ADAMTS13:AC levels were prognostic factors in patients with LC [2,14].