A previous study reported that VWF:Ag has become a useful diagnostic biomarker of PHT [23,24]; moreover, our previous study revealed that the ratio of VWF:Ag to ADAMTS13:AC (VWF:Ag/ADAMTS13:AC) has become a useful predictive biomarker of the development of ACLF [13]. Here, VWF is linked to pulmonary hypertension, primary, 1.