SNP rs883871 is a strong chromatin QTL in lymphoblastoid cell lines (LCLs) [44], overlaps the binding sites of numerous transcription factors (TFs) in the LCL GM12787 [43], is predicted to disrupt a consensus motif for the ETS family of TFs, which share a core “CCGGAA” motif, and is the lead SNP for a Multiple Sclerosis GWAS association [45]; variants in ETS1 itself have been previously associated with multiple sclerosis [46]. The gene discussed is ETS1; the disease is multiple sclerosis.