PDGFRA was highly upregulated in GBM compared with normal brain tissue samples (Fig. 4F), and Kaplan–Meier analysis of TCGA and CGGA datasets revealed that patients with PDGFRAhigh GBM exhibited shorter median overall survival relative to patients with PDGFRAlow GBM (Fig. 4G). The gene discussed is PDGFRA; the disease is glioblastoma.