In particular, we found an association between plasma proteins elevated in severe COVID-19, such as HGF, AREG, CKAP4, S100A12, NCF2, ITGB6, and a subpopulation of monocytes with lower expression of CD86 and HLA-DR, which are characteristics of myeloid-derived suppressor-like cells (Figure S8A). The gene discussed is ITGB6; the disease is COVID-19.