Metascape database analysis revealed that the target mRNAs PRKACB and PDCD4 of miR-550a-3p as well as RPS6KA5 and BCL2L2 of miR-550a-5p were associated with miRNA cancer pathway, providing important clues for subsequent studies on the mechanism underlying EAC development. The gene discussed is BCL2L2; the disease is cancer.