In leukemia (acute myelocytic leukemia), Wt1 (+KTS) can promote cancer cell proliferation, whereas Wt1 (−KTS) inhibited cell growth and proliferation and promoted cell apoptosis due to the expression of genes encoding the apoptosis regulator Caspase 9 [36, 37]. This evidence concerns the gene CASP9 and acute myeloid leukemia.