The most common TRAEs were AST increased (63 [43.2%]), ALT increased (54 [37.0%]), blood creatine phosphokinase increased (51 [34.9%]), hypercholesterolemia (49 [33.6%]), hypertriglyceridemia (39 [26.7%]), and hypertension (26 [17.8%]). The gene discussed is GPT; the disease is hypertriglyceridemia.