MGAT5 and posterior cortical atrophy: Interestingly, publicly available data28 demonstrates that several enzymes involved in the synthesis of these multiantennary structures, particularly MGAT4B, MGAT5, and MGAT5B, show aberrant upregulation in CRPC compared to hormone-sensitive PCa (Supplementary Fig. 10) suggesting increased expression of these enzymes might contribute to this observed phenotype.