We could validate this result in the HPV-negative TCGA-HNSCC data, showing significant correlations between CNAs and transcription levels of TP63 (r = 0.19, P = 2.5 × 10–3) and ATP1B3 (r = 0.37, P = 2.0 × 10–9) (Fig. 2f). The gene discussed is TP63; the disease is head and neck squamous cell carcinoma.