In the “≥60 years” subgroup, both KIF13B-exon4-SE and UBE2B-exon7-SE were differentially spliced between TB patients and HCs (ΔPSI = 0.10, P = 0.030; ΔPSI = 0.16, P < 0.001) (Supplementary Fig. S3, c). Here, UBE2B is linked to tuberculosis.