Using qPCR, we successfully validated several key genes regarding CD11c-associated molecules (Itgax, Gpnmb, Gpx3, Csf1, Spp1, Igf1) in the sham group, Day 7, Day 14, and Day 30 after ischemic stroke (Fig. 3D). The gene discussed is GPNMB; the disease is ischemic stroke.