TNF and alkaline phosphatase measurement: However, there seemed to be no significant difference in pancreatic pathological scores (Fig. 3A), expression of pancreatic and serum IL-6 and TNF-α (Fig. 3B and Supplementary Fig. 3), gross morphology of the pancreas (Fig. 3C), serum amylase (Fig. 3D), and the ratio of pancreas weight to body weight (Fig. 3E) between WT and Ripk3-/- mice with AP.