We synthesized the peptides identified by NAPA (Supplementary Table 7) and stimulated peripheral blood mononuclear cells (PBMCs) from ACPA+SE+ RA patients (n = 10), ACPA–SE+ RA patients (n = 8), and SE+ healthy controls (n = 10) with peptides from each peptide group (i.e., created/enhanced, no change, and destroyed). The gene discussed is PRTN3; the disease is rheumatoid arthritis.