MUC5AC and pancreatic intraductal papillary-mucinous neoplasm: In contrast, KSC mice consistently showed abundant and large IPMN lesions that exhibit high reactivity to the anti-Muc5AC antibody and Alcian blue (Fig. 7 B), which is in agreement with previous studies that KSC mice develop IPMN premalignant lesions rather than PanIN lesions (Bardeesy et al., 2006b; Izeradjene et al., 2007; Whittle et al., 2015).