Baumann L. et al in 2005 [11] reported their experience in the use of BoNT-B (Myobloc®) for palmar hyperhidrosis, through a double-blind, randomized, placebo-controlled study, including twenty patients (10 men and 10 women) diagnosed with palmar hyperhidrosis, who were injected with either Myobloc® (5000 U per palm) or a 1.0 mL vehicle (100 mM NaCl, 10 mM succinate, and 0.5 mg/mL human albumin) into bilateral palms (15 patients received Myobloc® and 5 received the placebo). This evidence concerns the gene ALB and Hyperhidrosis.