In addition, a posthoc analysis of the Chronic Kidney Insufficiency Cohort Study (CRIC study) in non-terminal chronic kidney disease (CKD) patients found that patients who had high baseline plasma titers of C-terminal FGF23 had an increased risk of first-time hospitalization with a severe infection, including pneumonia, urinary tract infection, and septicemia [17]. The gene discussed is FGF23; the disease is chronic kidney disease.