,23,24 Relative to KCs, the non-KC macrophages showed much lower expression for the markers CD163 (Figures 5G and 7A), CD206 (Figures 5H and 7B), MHCII (Figures 5I and 7C), CD11b (Figures 5J and 7D), and F4/80 (Figures 5K and 7E) in Shp2ΔH and Shp2ΔHK livers, suggesting that the non-KC macrophages were less differentiated than KCs. Here, ITGAM is linked to keratoconus.