ALB and colitis: To date, we have observed mice lacking FXR specifically in intestinal epithelial cells (FXRFl/FL-Vil-CRE) or in hepatocytes (FXRFl/FL-Alb-CRE) are both fully protected against DSS colitis by psyllium (Figure 13) and are currently generating mice to test the role of DC FXR in psyllium’s protection against colitis.