In infected patients, TSPAN8 expression decreases in airway brushes of acute illness in patients caused by non-SARS-CoV-2 respiratory viruses, while airway brushes from COVID-19 patients revealed preservation of TSPAN8 levels (Figure 5J), despite depletion in goblet cells (Mick et al., 2020). This evidence concerns the gene TSPAN8 and COVID-19.