By comparing HCC biopsies with non-cancerous adjacent tissues, miR-200a-3p and miR-27a/b were found significantly downregulated in cancer specimens, suggesting an inverse correlation between TIA-1/MFF mRNAs and miR-200a-3p/miR-27a, and underscoring their potential as novel biomarkers in HCC [73]. This evidence concerns the gene TIA1 and hepatocellular carcinoma.