Supporting the potential link between miR-148a-3p and mitochondrial dysfunction, the authors showed that miR-148a-3p downregulation in cisplatin-resistant gastric cancer cells was accompanied by upregulation of AKAP1, a direct miR-148a-3p downstream target, which antagonized cisplatin-induced mitochondrial fission, promoting PKA-dependent Drp1 phosphorylation at S637. This evidence concerns the gene AKAP1 and gastric cancer.