To explore the mechanisms underlying cisplatin-dependent deregulation of miR-593-5p, the authors investigated the miR-593-5p transcriptional regulation, analyzing a 5-kb upstream region of miR-593-5p, and identifying putative binding sites for BRCA1, suggesting the involvement of this tumor suppressor in the positive regulation of miR-593-5p. Here, BRCA1 is linked to neoplasm.