In a different approach aiming to demonstrate the presence of linc-ROR in intercellular exosomes, Takahashi et al. [128] demonstrated that linc-ROR is a hypoxia-responsive lncRNA in hepatocellular cancer (HCC) by sponging miR-145, generating intercellular signaling to promote cell survival during hypoxic stress. Here, LINC-ROR is linked to hepatocellular carcinoma.