CPEB3 and intrahepatic cholangiocarcinoma: So, due to its regulation of Gdf9 expression in oocytes, CPEB3 is crucial for the growth of ovarian follicles and female fertility.[27] hsa_circ_0050898, which was derived from the ACTN4 gene’s exons 1 to exons 20, was overexpressed in intrahepatic cholangiocarcinoma.