And, among 55 differentially expressed mRNA in circRNA/lncRNA–miRNA–mRNA network, CPEB3, EFNB3, FATA4, growth hormone receptor, GSTZ1, KLF8, MFAP4, PAIP2B, PHACTR3, PITPNM3, RPS6KA6, RSPO3, SLITRK6, SMOC1, STEAP4, SYT1, TMEM132E, TSPAN11, and ZFPM2 were intimately related to the prognosis of HCC patients in Kaplan–Meier plotter analysis (P < .05). The gene discussed is PITPNM3; the disease is hepatocellular carcinoma.