When the patient was previously studied at other medical centers, alterations of the Autoimmune regulator (AIRE) gene supporting a possible diagnosis of Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal-Distrophy (APECED), and a deficit of phagocyte bactericidal function assessed by nitro-blue tetrazolium test was ruled out. The gene discussed is AIRE; the disease is Candidiasis, Invasive.