The pie chart shows the percentage of expression of each isoform of tRFs/tiRNAs in the two groups of samples; we found that the CHD group mainly increased the expression of tRF-5a, tRF-5b and tRF-1, and decreased the expression of tiRNA-5 and tRF-3b and tRF-5c (Figure 2e,f). Here, TERF1 is linked to coronary artery disorder.