Existing studies have shown that the lack of KAT7 can lead to abnormal brain development19, and it has also been confirmed to be associated with gastric cancer (Jie et al. 2020), colon cancer (Taniue et al. 2020), non-small cell lung cancer (Gao et al. 2021), rheumatoid arthritis (Gao et al. 2017), and other diseases. This evidence concerns the gene KAT7 and malignant colon neoplasm.