The ten highest-scored genes (including CD163, FN1, FCGR3A, ITGB3, SERPINE1, THBS1, ITGA2B, CD14, MMP2, and CCR1) in the network were identified as the hub genes on the basis of the “MCC” algorithm, which are shown in Figure 10B. Subsequently, we analyzed CD163 expression level in AML patients by GEPIA dataset. Here, SERPINE1 is linked to acute myeloid leukemia.